HitPredict

Interactor 1: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.902

Property	Details
Experiments	9730828, 8294464, 28514442, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 205
+	Hs
		642738 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		642743 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		642722 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		642730 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		642718 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		642721 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		622577 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		622608 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		622619 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		622576 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		622590 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		622570 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		622574 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Mm
		838709 GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49		RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00
+	Hs
		678344 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Sc
		350882 GDI1_YEAST (176-597): 4.18e-144: 428: 23.72		YPT1_YEAST (4-205): 8.39e-81: 240: 70.39
+	Hs
		678343 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		678359 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		678336 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		678341 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86