HitPredict

Interactor 1: S10A4 (P26447)
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
Gene: S100A4

Interactor 2: HTRA4 (P83105)
Serine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4)
Gene: HTRA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31470122
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 476
+	Hs
		638947 S100P_HUMAN (3-96): 6.88e-35: 116: 41.49		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		416606 S10A6_HUMAN (1-92): 1.7e-28: 100: 50.00		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		416401 S10A9_HUMAN (3-91): 3.65e-28: 99.9: 31.11		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		949041 S10AG_HUMAN (3-83): 1.43e-23: 87.9: 37.81		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		949045 S10AD_HUMAN (3-84): 4.72e-22: 84.1: 34.15		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		949062 S10AE_HUMAN (3-84): 7.11e-20: 78.7: 28.05		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		949028 S1A7A_HUMAN (3-93): 5.2e-19: 76.4: 25.81		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		678434 S10A7_HUMAN (3-93): 4.96e-18: 74.1: 23.66		HTRA4_HUMAN (1-476): 0: 523: 100.00
+	Hs
		642924 S10A4_HUMAN (1-101): 9.21e-39: 126: 100.00		CCN3_HUMAN (39-159): 6.87e-29: 118: 28.35