Protein: KCNB2
Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2)

Gene: KCNB2
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q92953

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0006940 - regulation of smooth muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1370935

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

16

High-throughput

0.811

High

1351409

KCNG4
Voltage-gated potassium channel regulatory subunit KCNG4

2

18

Small-scale

0.783

High

1370937

KCNF1
Voltage-gated potassium channel regulatory subunit KCNF1

1

16

High-throughput

0.691

High

1370942

KCNG1
Voltage-gated potassium channel regulatory subunit KCNG1

1

16

High-throughput

0.691

High

1131512

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

16

Small-scale

0.621

High

1347017

KCNG3
Voltage-gated potassium channel regulatory subunit KCNG3

1

18

Small-scale

0.621

High

1370932

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

16

Small-scale

0.621

High

1004154

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.618

High

1244866

KCNV1
Potassium voltage-gated channel subfamily V member 1

1

18

Small-scale

0.618

High

540606

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

281387

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.489

High

1288354

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

High-throughput

0.489

High

189758

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

291472

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

299322

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

341119

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.479

High

375808

RASK
GTPase KRas

1

3

High-throughput

0.479

High

417651

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

418327

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

463692

LYN
Tyrosine-protein kinase Lyn

1

10

High-throughput

0.479

High

562285

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

601398

RHOQ
Rho-related GTP-binding protein RhoQ

1

1

High-throughput

0.479

High

604141

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

614716

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

High-throughput

0.479

High

880635

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.479

High

894951

EMD
Emerin

1

2

High-throughput

0.479

High

904046

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

910155

RND2
Rho-related GTP-binding protein RhoN

1

4

High-throughput

0.479

High

936406

AFAD
Afadin

1

20

High-throughput

0.479

High

962800

RND3
Rho-related GTP-binding protein RhoE

1

4

High-throughput

0.479

High

987832

GRB2
Growth factor receptor-bound protein 2

1

13

High-throughput

0.479

High

1122302

SCRIB
Protein scribble homolog

1

20

Small-scale

0.479

High

1151810

RHOH
Rho-related GTP-binding protein RhoH

1

2

High-throughput

0.479

High

1159790

OCLN
Occludin

1

1

High-throughput

0.479

High

1229023

RNF43
E3 ubiquitin-protein ligase RNF43

1

6

High-throughput

0.479

High

1286424

AMGO2
Amphoterin-induced protein 2

1

7

Small-scale

0.479

High

1292540

AMGO1
Amphoterin-induced protein 1

1

7

Small-scale

0.479

High

1292573

AMGO3
Amphoterin-induced protein 3

1

6

Small-scale

0.479

High

1322930

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1366858

RND1
Rho-related GTP-binding protein Rho6

1

3

High-throughput

0.479

High

1370938

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1370941

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1370943

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

180005

BET1
BET1 homolog

1

0

High-throughput

0.458

High

218580

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

327395

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

580668

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

976469

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1370933

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.458

High

1370934

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1370936

DERL1
Derlin-1

1

0

High-throughput

0.458

High

956435

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.437

High

1370939

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.437

High

1370940

VAPA
Vesicle-associated membrane protein-associated protein A

1

8

Small-scale

0.408

High


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Last updated: 11Aug2025