Interactor 1: BUB3 (P26449)
Cell cycle arrest protein BUB3
Gene: BUB3
Interactor 2: BUB1 (P41695)
Checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1)
Gene: BUB1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17227844, 11283351, 7969164, 10837255, 15644329, 27618268, 18719252, 37968396, 10704439, 12221113, 17634282, 20489023, 24066227, 23267104, 10688190, 16429126 |
| Identification Methods | isothermal titration calorimetry, two hybrid pooling approach, coimmunoprecipitation, x-ray crystallography, affinity chromatography technology, two hybrid, enzymatic study, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation and 2 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Mad3_BUB1_I~WD40, Mad3_BUB1_II~WD40 |
| Common GO terms | GO:0000776 - kinetochore GO:0007094 - mitotic spindle assembly checkpoint signaling GO:1990298 - bub1-bub3 complex |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
