Protein: NUG1
Nuclear GTP-binding protein NUG1 (Nuclear GTPase 1)

Gene: NUG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 212
UniProt ID: P40010

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

766673

NOG2
Nucleolar GTP-binding protein 2

11

2

Small-scale

0.973

High

754125

CIC1
Proteasome-interacting protein CIC1

8

2

Small-scale

0.961

High

766648

NOP2
25S rRNA

12

2

Small-scale

0.756

High

766691

ARX1
Probable metalloprotease ARX1

13

5

Small-scale

0.756

High

756824

RIX1
Pre-rRNA-processing protein RIX1

13

1

Small-scale

0.756

High

766670

PESC
Pescadillo homolog

12

1

Small-scale

0.756

High

733832

RPF2
Ribosome biogenesis protein RPF2

11

2

Small-scale

0.755

High

766716

BUD20
Bud site selection protein 20

9

2

Small-scale

0.753

High

766687

NOG1
Nucleolar GTP-binding protein 1

11

9

Small-scale

0.753

High

766699

ERB1
Ribosome biogenesis protein ERB1

9

11

Small-scale

0.750

High

766671

SDA1
Protein SDA1

9

2

Small-scale

0.748

High

766735

DBP10
ATP-dependent RNA helicase DBP10

8

7

Small-scale

0.748

High

764186

NOC2
Nucleolar complex protein 2

9

1

Small-scale

0.748

High

766689

HAS1
ATP-dependent RNA helicase HAS1

9

18

Small-scale

0.745

High

630866

NLE1
Ribosome assembly protein 4

8

7

Small-scale

0.744

High

766714

NOC3
Nucleolar complex-associated protein 3

8

5

Small-scale

0.744

High

766678

NOP15
Ribosome biogenesis protein 15

7

7

High-throughput

0.744

High

766637

NSA2
Ribosome biogenesis protein NSA2

7

4

Small-scale

0.742

High

766726

MDN1
Midasin

7

5

Small-scale

0.740

High

766667

LSG1
Large subunit GTPase 1

2

2

Small-scale

0.737

High

742019

NOP4
Nucleolar protein 4

6

3

Small-scale

0.731

High

634413

SPB1
27S pre-rRNA

6

6

Small-scale

0.728

High

535005

RL3
Large ribosomal subunit protein uL3

6

3

Small-scale

0.726

High

638763

SPB4
ATP-dependent rRNA helicase SPB4

6

18

High-throughput

0.726

High

640961

RL5
Large ribosomal subunit protein uL18

6

5

Small-scale

0.726

High

766646

RLP7
Ribosome biogenesis protein RLP7

6

8

Small-scale

0.721

High

766728

NOP53
Ribosome biogenesis protein NOP53

6

3

Small-scale

0.721

High

766650

LOC1
60S ribosomal subunit assembly/export protein LOC1

5

1

Small-scale

0.711

High

766697

PUF6
Pumilio homology domain family member 6

5

1

Small-scale

0.706

High

731816

EBP2
rRNA-processing protein EBP2

5

1

High-throughput

0.704

High

703056

MRT4
Ribosome assembly factor MRT4

5

6

Small-scale

0.702

High

766676

IPI3
Pre-rRNA-processing protein IPI3

5

10

Small-scale

0.702

High

766653

ALB1
Ribosome biogenesis protein ALB1

4

2

Small-scale

0.686

High

766727

YTM1
Ribosome biogenesis protein YTM1

4

11

High-throughput

0.686

High

766736

IF6
Eukaryotic translation initiation factor 6

4

5

Small-scale

0.686

High

766669

CGR1
rRNA-processing protein CGR1

4

2

Small-scale

0.685

High

754864

SSF1
Ribosome biogenesis protein SSF1

4

2

Small-scale

0.676

High

766666

NSA1
Ribosome biogenesis protein NSA1

4

1

Small-scale

0.676

High

766693

RRP17
Ribosomal RNA-processing protein 17

4

1

High-throughput

0.676

High

766715

RLP24
Ribosome biogenesis protein RLP24

4

5

Small-scale

0.676

High

383171

RL25
Large ribosomal subunit protein uL23

3

3

Small-scale

0.656

High

766704

FKBP4
FK506-binding protein 4

3

2

High-throughput

0.656

High

766724

NIP7
60S ribosome subunit biogenesis protein NIP7

3

1

Small-scale

0.656

High

481342

RL2A
Large ribosomal subunit protein uL2A

3

5

High-throughput

0.640

High

742818

GBLP
Small ribosomal subunit protein RACK1

3

15

Small-scale

0.640

High

766636

IMB4
Importin subunit beta-4

3

6

Small-scale

0.633

High

407080

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.618

High

766571

NOP16
Nucleolar protein 16

3

0

High-throughput

0.613

High

755290

RPF1
Ribosome production factor 1

2

1

High-throughput

0.611

High

766677

NOP13
Nucleolar protein 13

2

3

High-throughput

0.611

High

766718

BRX1
Ribosome biogenesis protein BRX1

2

9

High-throughput

0.611

High

766725

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.586

High

399485

RLA0
Large ribosomal subunit protein uL10

3

6

Small-scale

0.585

High

498944

RL4A
Large ribosomal subunit protein uL4A

2

9

Small-scale

0.584

High

645043

RL16A
Large ribosomal subunit protein uL13A

2

6

High-throughput

0.584

High

756350

NMD3
60S ribosomal export protein NMD3

2

1

Small-scale

0.584

High

766649

UTP10
U3 small nucleolar RNA-associated protein 10

2

2

High-throughput

0.584

High

766722

RS10A
Small ribosomal subunit protein eS10A

2

3

High-throughput

0.584

High

368096

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.575

High

645470

RS7A
Small ribosomal subunit protein eS7A

2

2

High-throughput

0.571

High

481923

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.553

High

679559

RM09
Large ribosomal subunit protein uL3m

2

6

High-throughput

0.537

High

735328

RM10
Large ribosomal subunit protein uL15m

2

2

High-throughput

0.537

High

471401

RL11A
Large ribosomal subunit protein uL5A

1

7

High-throughput

0.536

High

534773

RL30
Large ribosomal subunit protein eL30

1

3

High-throughput

0.536

High

550044

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.536

High

615153

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.536

High

667191

RL8B
Large ribosomal subunit protein eL8B

1

6

High-throughput

0.536

High

676082

XPO1
Exportin-1

1

5

High-throughput

0.536

High

696334

PP12
Serine/threonine-protein phosphatase PP1-2

1

2

High-throughput

0.536

High

766661

RL4B
Large ribosomal subunit protein uL4B

1

9

High-throughput

0.536

High

766665

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

4

High-throughput

0.536

High

766672

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

766683

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

766733

RL7B
Large ribosomal subunit protein uL30B

1

8

High-throughput

0.536

High

766686

SKI8
Antiviral protein SKI8

1

11

High-throughput

0.515

High

664464

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

766657

YMR1
Phosphoinositide 3-phosphatase

1

0

High-throughput

0.513

High

766694

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

766711

TSR1
Ribosome biogenesis protein TSR1

1

0

High-throughput

0.513

High

766713

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

743545

HMT1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.501

High

659791

SBA1
Co-chaperone protein SBA1

1

0

High-throughput

0.493

High

766663

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.493

High

424537

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.489

High

766660

RL38
Large ribosomal subunit protein eL38

1

2

High-throughput

0.489

High

141356

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

366347

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

376798

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.479

High

392442

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

404598

RL7A
Large ribosomal subunit protein uL30A

1

8

High-throughput

0.479

High

405646

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.479

High

406543

RL22A
Large ribosomal subunit protein eL22A

1

5

High-throughput

0.479

High

407942

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

408374

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

410392

SC160
Protein SCP160

1

3

High-throughput

0.479

High

413528

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

425974

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.479

High

480126

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.479

High

481645

RL18B
Large ribosomal subunit protein eL18B

1

4

High-throughput

0.479

High

501220

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

558074

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

564300

RL8A
Large ribosomal subunit protein eL8A

1

6

Small-scale

0.479

High

594046

MAK11
Protein MAK11

1

10

High-throughput

0.479

High

606655

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

628098

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

631904

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

634619

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

662324

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

663871

TF3B
Transcription factor IIIB 70 kDa subunit

1

4

High-throughput

0.479

High

688260

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

698162

AFG2
ATPase family gene 2 protein

1

1

High-throughput

0.479

High

699686

DRS1
ATP-dependent RNA helicase DRS1

1

14

High-throughput

0.479

High

704348

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.479

High

710886

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

Small-scale

0.479

High

715446

RRP1
Ribosomal RNA-processing protein 1

1

3

High-throughput

0.479

High

729935

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

732728

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

746242

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

748618

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

752480

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

755229

IPI1
Pre-rRNA-processing protein IPI1

1

2

High-throughput

0.479

High

757276

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

761946

DHH1
ATP-dependent RNA helicase DHH1

1

7

High-throughput

0.479

High

762229

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

766642

BMT5
25S rRNA

1

1

High-throughput

0.479

High

766645

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

766651

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

766654

MTR4
ATP-dependent RNA helicase DOB1

1

7

Small-scale

0.479

High

766656

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

766659

RL37A
Large ribosomal subunit protein eL37A

1

3

High-throughput

0.479

High

766662

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

766674

JJJ1
J protein JJJ1

1

11

Small-scale

0.479

High

766675

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.479

High

766679

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

766680

RCM1
25S rRNA

1

2

High-throughput

0.479

High

766681

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

766684

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

766688

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

766692

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

766695

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

766696

RRB1
Ribosome assembly protein RRB1

1

7

High-throughput

0.479

High

766698

UTP14
U3 small nucleolar RNA-associated protein 14

1

3

High-throughput

0.479

High

766700

RRP5
rRNA biogenesis protein RRP5

1

3

High-throughput

0.479

High

766701

HRQ1
ATP-dependent helicase HRQ1

1

6

Small-scale

0.479

High

766702

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

766705

JIP5
WD repeat-containing protein JIP5

1

9

High-throughput

0.479

High

766706

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

766708

NOC4
Nucleolar complex protein 4

1

9

High-throughput

0.479

High

766709

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.479

High

766717

NOP12
Nucleolar protein 12

1

6

High-throughput

0.479

High

766719

SGO1
Shugoshin

1

2

High-throughput

0.479

High

766720

TMA16
Translation machinery-associated protein 16

1

2

High-throughput

0.479

High

766723

RRS1
Regulator of ribosome biosynthesis

1

2

High-throughput

0.479

High

766729

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

766730

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

766731

MAK21
Ribosome biogenesis protein MAK21

1

9

High-throughput

0.479

High

766732

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

608466

SAN1
Protein SAN1

1

0

Small-scale

0.458

High

622874

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.458

High

630201

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

691056

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

732218

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

764952

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

766644

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

766655

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

766703

YL455
PWWP domain-containing protein YLR455W

1

0

High-throughput

0.458

High

766707

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

766734

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

491340

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

494063

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

511444

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

694771

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

746293

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.445

High

761364

XDJ1
DnaJ protein homolog XDJ1

1

3

High-throughput

0.445

High

766638

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

766685

NU116
Nucleoporin NUP116/NSP116

1

1

Small-scale

0.445

High

766690

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.445

High

358087

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

471079

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

471783

RL27A
Large ribosomal subunit protein eL27A

1

3

High-throughput

0.437

High

472214

RL31A
Large ribosomal subunit protein eL31A

1

6

High-throughput

0.437

High

479118

RL43B
Large ribosomal subunit protein eL43B

1

4

High-throughput

0.437

High

480692

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

482282

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

543804

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.437

High

700436

RSSA1
Small ribosomal subunit protein uS2A

1

5

High-throughput

0.437

High

706296

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

748141

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.437

High

766640

MLP2
Protein MLP2

1

2

High-throughput

0.437

High

766643

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.437

High

766658

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

766682

NUM1
Nuclear migration protein NUM1

1

5

High-throughput

0.437

High

766712

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

592911

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

766710

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.426

High

479031

RL43A
Large ribosomal subunit protein eL43A

1

4

High-throughput

0.407

High

535230

RS17B
Small ribosomal subunit protein eS17B

1

3

High-throughput

0.407

High

760867

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

766652

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

766647

CIN1
Chromosome instability protein 1

1

0

High-throughput

0.279

Low

766664

NBP1
NAP1-binding protein

1

0

Small-scale

0.279

Low

766668

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

766721

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

747693

YSW1
Spore-specific protein YSW1

1

0

High-throughput

0.269

Low

446164

MYO1
Myosin-1

1

0

Small-scale

0.249

Low

700919

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

732293

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

766641

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

748448

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low

751367

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.232

Low

766639

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024