HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 209 Hs			1 130
+	Hs
		449745 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Hs
		449762 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		643395 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66
+	Hs
		594829 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		H2A1D_HUMAN (1-130): 7.72e-67: 199: 97.69
+	Hs
		1151386 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Hs
		391917 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470568 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Sc
		392263 NHP6A_YEAST (75-164): 2.99e-25: 96: 44.44		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		1087107 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Sc
		392264 NHP6B_YEAST (73-164): 5.93e-24: 92.9: 42.39		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		555655 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392030 NHP6A_YEAST (75-164): 2.99e-25: 96: 44.44		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25
+	Sc
		392031 NHP6B_YEAST (73-164): 5.93e-24: 92.9: 42.39		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25
+	Hs
		996711 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Ce
		136713 SSP1B_CAEEL (91-196): 3.14e-20: 89.8: 31.13		Q27485_CAEEL (17-121): 1.89e-54: 168: 90.48
+	Sc
		392374 IXR1_YEAST (79-209): 2.58e-16: 78.6: 21.37		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		391670 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470362 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		996693 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		555429 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81