Protein: OSBL5
Oxysterol-binding protein-related protein 5 (ORP-5) (OSBP-related protein 5) (Oxysterol-binding protein homolog 1)

Gene: OSBL5, OSBPL5
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9H0X9

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0005548 - phospholipid transporter activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006893 - Golgi to plasma membrane transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1419777

OSBL8
Oxysterol-binding protein-related protein 8

5

12

Small-scale

0.919

High

1103795

PLD1
Phospholipase D1

2

0

High-throughput

0.770

High

854287

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.691

High

922284

LIMK1
LIM domain kinase 1

1

7

High-throughput

0.691

High

1116003

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.691

High

932387

ANAG
Alpha-N-acetylglucosaminidase

3

1

High-throughput

0.662

High

1393159

PRR11
Proline-rich protein 11

3

0

High-throughput

0.634

High

572957

INSRR
Insulin receptor-related protein

1

20

High-throughput

0.618

High

362372

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.618

High

1140833

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.618

High

391456

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

1333282

KLH23
Kelch-like protein 23

2

4

High-throughput

0.574

High

733071

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

1

High-throughput

0.549

High

835384

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

1

High-throughput

0.549

High

161836

RIOK3
Serine/threonine-protein kinase RIO3

1

2

High-throughput

0.536

High

1049768

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1126363

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

2

High-throughput

0.536

High

189276

IPO8
Importin-8

1

0

High-throughput

0.513

High

922501

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

1292482

LHPL1
LHFPL tetraspan subfamily member 1 protein

1

0

High-throughput

0.513

High

1430725

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.513

High

169745

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

Small-scale

0.501

High

423135

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

868313

P2RY1
P2Y purinoceptor 1

1

4

High-throughput

0.489

High

1339938

OR1M1
Olfactory receptor 1M1

1

2

High-throughput

0.489

High

1415226

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.489

High

1430722

TMM9B
Transmembrane protein 9B

1

2

High-throughput

0.489

High

791710

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

954412

SNP25
Synaptosomal-associated protein 25

1

8

Small-scale

0.481

High

164439

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

178392

NPC1
NPC intracellular cholesterol transporter 1

1

1

Small-scale

0.479

High

1045755

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1367236

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1404195

SEC62
Translocation protein SEC62

1

5

High-throughput

0.479

High

133795

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

1208412

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

0

Small-scale

0.458

High

1199034

KLH12
Kelch-like protein 12

1

3

High-throughput

0.445

High

1236310

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

1272743

MAEA
E3 ubiquitin-protein transferase MAEA

1

1

High-throughput

0.445

High

1346783

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.445

High

1350063

SPP2B
Signal peptide peptidase-like 2B

1

3

High-throughput

0.445

High

1430721

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

1

High-throughput

0.445

High

1430724

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.445

High

1383463

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.426

High

166410

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

6

High-throughput

0.407

High

616807

SDC1
Syndecan-1

1

3

High-throughput

0.407

High

760499

SDC2
Syndecan-2

1

3

High-throughput

0.407

High

935980

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.407

High

1337947

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

1402517

NEB2
Neurabin-2

1

3

High-throughput

0.407

High

239203

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

848175

MAGA1
Melanoma-associated antigen 1

1

0

High-throughput

0.279

Low

1212458

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.279

Low

1430723

KLC4
Kinesin light chain 4

1

0

High-throughput

0.279

Low

1430727

ZN281
Zinc finger protein 281

1

0

High-throughput

0.279

Low

1430726

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025