HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: NOP53 (Q9NZM5)
Ribosome biogenesis protein NOP53 (Glioma tumor suppressor candidate region gene 2 protein) (Protein interacting with carboxyl terminus 1) (PICT-1) (p60)
Gene: NOP53

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	31694235, 32867128
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 478
+	Hs
		818544 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		NOP53_HUMAN (1-478): 1.73e-151: 441: 100.00
+	Hs
		567780 UBF1_HUMAN (10-158): 1.47e-09: 58.9: 24.72		NOP53_HUMAN (1-478): 1.73e-151: 441: 100.00