HitPredict

Interactor 1: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Interactor 2: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 25416956, 16189514, 10772858, 9563502, 37071682
Identification Methods two hybrid, pull down, cross-linking study, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~RRM_5, RRM_5~RRM_5, RRM_8~RRM_8
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 557
Hs

1 557
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024