Interactor 1: FEN1 (P26793)
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (RAD2 homolog nuclease 1) (RTH1 nuclease) (Structure-specific endonuclease RAD27)
Gene: RAD27

Interactor 2: DNA2 (P38859)
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]
Gene: DNA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 9121462, 20628185
Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0017108 - 5'-flap endonuclease activity
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 382
Sc

1 1522
+ Hs
+ Sp
+ Hs
+ Sc
+ Mm
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024