Protein: MKT1
Post-transcriptional regulator MKT1 (Inactive endonuclease MKT1)

Gene: MKT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: P40850

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003730 - mRNA 3'-UTR binding
GO:0004520 - DNA endonuclease activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

524220

HSP71
Heat shock protein SSA1

4

2

High-throughput

0.672

High

626772

HSP60
Heat shock protein 60, mitochondrial

4

0

High-throughput

0.658

High

526915

HSP72
Heat shock protein SSA2

3

2

High-throughput

0.624

High

736855

APE2
Aminopeptidase 2, mitochondrial

2

0

High-throughput

0.585

High

796872

GID4
GID complex substrate-recognition subunit 4

2

0

High-throughput

0.585

High

828327

MCA1
Metacaspase-1

2

0

Small-scale

0.585

High

670814

SIS1
Protein SIS1

2

1

High-throughput

0.584

High

676074

MAS5
Mitochondrial protein import protein MAS5

2

1

High-throughput

0.571

High

828330

HSP42
Heat shock protein 42

2

1

High-throughput

0.571

High

828304

PBP1
PAB1-binding protein 1

1

1

Small-scale

0.552

High

574692

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.536

High

734313

DBF20
Serine/threonine-protein kinase DBF20

1

1

High-throughput

0.536

High

828309

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

1

High-throughput

0.536

High

828310

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.536

High

417122

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.513

High

448591

RHO2
GTP-binding protein RHO2

1

0

High-throughput

0.513

High

460984

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

575349

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.513

High

639558

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

0

High-throughput

0.513

High

656322

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

High-throughput

0.513

High

660864

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

0

High-throughput

0.513

High

750853

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.513

High

805461

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.513

High

828317

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

828325

RBX1
RING-box protein HRT1

1

0

High-throughput

0.513

High

657098

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.493

High

668274

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.493

High

828305

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

High-throughput

0.493

High

645938

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.489

High

518316

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

585631

STI1
Heat shock protein STI1

1

1

High-throughput

0.479

High

645745

HSP74
Heat shock protein SSA4

1

2

High-throughput

0.479

High

741755

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.479

High

812055

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

828306

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

828329

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

1

High-throughput

0.479

High

149811

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

365077

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

366716

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.458

High

368454

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

368693

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

383743

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

402030

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

410181

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433690

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

435150

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436014

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

441959

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

450603

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.458

High

455108

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503092

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

504259

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

512487

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513056

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514678

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

531342

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

558760

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

572605

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

579560

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

618597

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.458

High

674672

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

679781

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

689509

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

727099

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

733665

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

734125

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

735016

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

740670

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.458

High

747416

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

747901

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

753420

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

760597

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.458

High

778372

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

779068

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.458

High

790420

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.458

High

792090

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

792356

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.458

High

802219

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815142

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

828296

SAS2
Histone acetyltransferase SAS2

1

0

Small-scale

0.458

High

828298

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.458

High

828299

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

828300

ACS2
Acetyl-coenzyme A synthetase 2

1

0

High-throughput

0.458

High

828302

CDH1
APC/C activator protein CDH1

1

0

Small-scale

0.458

High

828307

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.458

High

828311

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

828313

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

828315

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

828318

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

828321

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

828324

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

828326

SGO1
Shugoshin

1

0

High-throughput

0.458

High

828328

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

828333

SUS1
SAGA complex subunit SUS1

1

0

Small-scale

0.458

High

545199

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

590649

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

828316

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

828332

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

812233

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

828301

HOS2
Probable histone deacetylase HOS2

1

0

High-throughput

0.426

High

675341

RAD51
DNA repair protein RAD51

2

0

High-throughput

0.324

High

555261

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.279

Low

828303

YG2A
Zinc finger protein YGR067C

1

0

High-throughput

0.279

Low

828331

ARP7
Actin-related protein 7

1

0

High-throughput

0.269

Low

707343

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

734375

OAC1
Mitochondrial oxaloacetate transport protein

1

0

High-throughput

0.249

Low

764096

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

825795

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

826562

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

828297

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

828308

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

828312

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.249

Low

828319

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

828320

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

828322

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

828323

CDC73
Cell division control protein 73

1

0

High-throughput

0.249

Low

828314

WDR59
Maintenance of telomere capping protein 5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025