Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 33961781, 35271311, 34349018, 35235311, 24255178, 36931259, 37071682, 20618440, 17085597, 28514442
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, mass spectrometry studies of complexes, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0006605 - protein targeting
GO:0007165 - signal transduction
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 245
Hs

1 246
+ Hs
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+ At
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+ Sl
+ Zm
+ At
+ At
+ Mm
+ Dm
+ Hs
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+ Mm
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+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024