HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27913189
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 323
+	Mm
		926530 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP1G_MOUSE (1-323): 0: 602: 99.69
+	Bt
		898865 1433Z_BOVIN (1-245): 1.75e-141: 397: 79.59		PP1G_BOVIN (1-323): 0: 602: 99.69
+	Hs
		683174 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		905812 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Mm
		906225 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Mm
		906229 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Mm
		906231 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		PP1A_MOUSE (1-323): 0: 579: 90.36
+	At
		788328 14331_ARATH (3-242): 2.67e-142: 400: 61.07		PP15_ARATH (2-303): 0: 527: 77.56
+	Hs
		909432 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08
+	Mm
		915319 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP2AB_MOUSE (8-312): 2.02e-178: 497: 46.73
+	Hs
		905846 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		904418 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Mm
		905328 1433G_MOUSE (1-242): 5.48e-105: 305: 70.33		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Zm
		36330 B6U284_MAIZE (1-243): 2.35e-143: 403: 59.92		A0A1D6LZA4_MAIZE (1-310): 2.85e-149: 423: 62.58