Protein: APC4
Anaphase-promoting complex subunit 4

Gene: APC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: Q04601

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046881

APC5
Anaphase-promoting complex subunit 5

8

0

Small-scale

0.924

High

1046886

APC2
Anaphase-promoting complex subunit 2

7

0

Small-scale

0.914

High

827030

MND2
Anaphase-promoting complex subunit MND2

6

0

Small-scale

0.894

High

486791

CDC16
Anaphase-promoting complex subunit CDC16

18

2

Small-scale

0.764

High

597621

CDC23
Anaphase-promoting complex subunit CDC23

8

2

Small-scale

0.750

High

792483

CDC27
Anaphase-promoting complex subunit CDC27

7

1

Small-scale

0.747

High

916911

APC10
Anaphase-promoting complex subunit DOC1

7

0

Small-scale

0.716

High

1046878

APC4
Anaphase-promoting complex subunit 4

2

0

Small-scale

0.716

High

1046883

APC9
Anaphase-promoting complex subunit 9

6

0

Small-scale

0.702

High

924374

APC1
Anaphase-promoting complex subunit 1

6

0

Small-scale

0.701

High

1046884

APC11
Anaphase-promoting complex subunit 11

5

0

Small-scale

0.686

High

1046885

SWM1
Anaphase-promoting complex subunit SWM1

5

0

Small-scale

0.684

High

575049

CDC26
Anaphase-promoting complex subunit CDC26

4

0

Small-scale

0.664

High

918122

CDH1
APC/C activator protein CDH1

2

0

Small-scale

0.547

High

740009

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

Small-scale

0.513

High

364732

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

448799

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.460

High

557036

AAKG
5'-AMP-activated protein kinase subunit gamma

1

0

High-throughput

0.460

High

647834

RFA1
Replication factor A protein 1

1

0

Small-scale

0.460

High

677277

MET14
Karyogamy protein KAR4

1

0

High-throughput

0.460

High

745424

FZF1
Zinc finger protein FZF1

1

0

High-throughput

0.460

High

820862

ERG29
Ergosterol biosynthesis protein 29

1

0

High-throughput

0.460

High

1046879

DUS3
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]

1

0

High-throughput

0.460

High

1046887

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.460

High

1046882

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

1046888

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

525101

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527638

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

546220

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742365

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

819754

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

865961

DPH4
Diphthamide biosynthesis protein 4

1

1

High-throughput

0.445

High

646689

VPS15
Serine/threonine-protein kinase VPS15

1

1

High-throughput

0.437

High

393309

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

676337

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

795698

ECM13
Protein ECM13

1

0

High-throughput

0.251

Low

1046880

IMH1
Golgin IMH1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025