HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	12042314, 17470459, 14504289, 18281517
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 198
+	Hs
		804093 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00
+	Hs
		804097 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00
+	Hs
		683191 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00
+	Mm
		763414 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		CDN1A_MOUSE (17-167): 3.27e-48: 156: 27.27
+	Hs
		646695 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDN1A_HUMAN (17-167): 1.06e-46: 152: 27.10
+	Hs
		683889 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00
+	Hs
		804112 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00
+	Hs
		804092 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00