HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	21988832, 17353931, 33961781, 35271311, 36931259, 15324660, 15161933, 28514442
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1025
+	Hs
		909703 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Mm
		910229 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MPRIP_MOUSE (1-1024): 9.38e-118: 388: 88.01
+	Hs
		909845 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		647130 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		909680 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		647001 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		910040 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		647290 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		725130 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Mm
		926855 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Hs
		646681 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724761 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		647370 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH2_HUMAN (122-873): 5.69e-17: 89: 9.31
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Hs
		522602 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Mm
		926804 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH10_MOUSE (534-1014): 8.31e-16: 85.1: 9.18
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Mm
		926889 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60
+	Hs
		646909 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96