HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: LMO7 (Q8WWI1)
LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)
Gene: LMO7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	35271311, 36931259, 15161933
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1683
+	Hs
		909860 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LMO7_HUMAN (1-1683): 0: 1276: 100.00
+	Hs
		927344 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LMO7_HUMAN (1-1683): 0: 1276: 100.00
+	Hs
		683576 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		LMO7_HUMAN (1-1683): 0: 1276: 100.00
+	Hs
		684235 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LMO7_HUMAN (1-1683): 0: 1276: 100.00
+	Mm
		93299 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		E9PYF4_MOUSE (69-1683): 0: 1075: 75.72
+	Dm
		115063 1433E_DROME (2-242): 6.77e-143: 401: 65.02		M9PE30_DROME (55-213): 1.74e-39: 146: 28.83
+	Hs
		683177 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		TAGL2_HUMAN (49-204): 1.21e-40: 151: 21.39
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (573-1510): 1.73e-27: 124: 9.08
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (573-1510): 1.73e-27: 124: 9.08
+	Hs
		728466 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH11_HUMAN (573-1510): 1.73e-27: 124: 9.08
+	Hs
		306570 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		SCEL_HUMAN (1097-1674): 1.66e-54: 205: 12.85
+	Hs
		647370 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH2_HUMAN (647-1572): 1.28e-24: 114: 7.55
+	Hs
		927643 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH2_HUMAN (647-1572): 1.28e-24: 114: 7.55
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (532-1524): 3.32e-23: 110: 8.22
+	Hs
		522602 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH7_HUMAN (532-1524): 3.32e-23: 110: 8.22
+	Hs
		646909 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PLEC_HUMAN (529-1454): 9.61e-19: 95.9: 8.50
+	Hs
		927068 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PLEC_HUMAN (529-1454): 9.61e-19: 95.9: 8.50
+	Mm
		926889 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PLEC_MOUSE (864-1631): 1.26e-15: 85.5: 8.17
+	Hs
		683875 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MYH11_HUMAN (573-1510): 1.73e-27: 124: 9.08
+	Hs
		684048 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		PLEC_HUMAN (529-1454): 9.61e-19: 95.9: 8.50