HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KPCD2 (Q9BZL6)
Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)
Gene: PRKD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 878
+	Hs
		909585 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		646908 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		927067 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		566293 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCA_HUMAN (103-867): 0: 571: 17.41
+	Hs
		566348 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCA_HUMAN (103-867): 0: 571: 17.41
+	Hs
		397155 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCG_HUMAN (124-867): 2.66e-179: 535: 16.97
+	Hs
		681770 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKT1_HUMAN (400-876): 6.74e-149: 449: 22.00
+	Hs
		681776 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		AKT1_HUMAN (400-876): 6.74e-149: 449: 22.00
+	At
		965360 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CIPKC_ARATH (527-861): 2.25e-115: 362: 28.07
+	At
		788672 14333_ARATH (3-243): 8e-143: 401: 61.63		CIPKC_ARATH (527-861): 2.25e-115: 362: 28.07
+	At
		1280891 14337_ARATH (2-243): 2.78e-142: 400: 60.32		CIPKC_ARATH (527-861): 2.25e-115: 362: 28.07
+	Hs
		909458 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCE_HUMAN (74-387): 2.68e-61: 223: 19.51
+	Hs
		646812 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCE_HUMAN (74-387): 2.68e-61: 223: 19.51
+	Hs
		926942 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCE_HUMAN (74-387): 2.68e-61: 223: 19.51
+	Hs
		646820 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCT_HUMAN (90-400): 2.14e-57: 211: 16.88
+	Hs
		909811 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DCLK2_HUMAN (534-809): 1.65e-43: 171: 37.59
+	Mm
		910275 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DCLK2_MOUSE (534-809): 3.37e-43: 170: 37.59
+	Hs
		647105 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DCLK2_HUMAN (534-809): 1.65e-43: 171: 37.59
+	Hs
		909532 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2D_HUMAN (549-812): 2.35e-41: 160: 36.57
+	Mm
		926819 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2D_MOUSE (549-812): 2.35e-41: 160: 36.57