HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PKHA3 (Q9HB20)
Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)
Gene: PLEKHA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 300
+	Hs
		910042 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		927547 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		909582 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ACAP2_HUMAN (1-300): 6.71e-44: 161: 16.88
+	Hs
		909680 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		982516 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		647001 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	At
		788659 14333_ARATH (3-243): 8e-143: 401: 61.63		DRP2A_ARATH (3-287): 9.8e-38: 144: 16.27
+	Hs
		927168 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		683445 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		910172 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		647389 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		927669 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		683824 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Mm
		935568 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		OSB11_MOUSE (1-298): 2.08e-42: 157: 16.62
+	Hs
		684430 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		CERT_HUMAN (3-252): 4.02e-40: 149: 19.81
+	Hs
		684119 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		982141 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		684404 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		982447 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSB10_HUMAN (1-298): 7.33e-34: 132: 16.14
+	Hs
		982632 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09