Protein: SPB12
Serpin B12

Gene: SPB12, SERPINB12
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q96P63

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629169

ZA2G
Zinc-alpha-2-glycoprotein

1

2

High-throughput

0.618

High

714770

TRY3
Trypsin-3

1

20

High-throughput

0.618

High

1299100

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.618

High

529588

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.536

High

988120

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.536

High

992034

BAX
Apoptosis regulator BAX

1

2

High-throughput

0.536

High

1060878

IMB1
Importin subunit beta-1

1

1

High-throughput

0.536

High

1187464

APTX
Aprataxin

1

3

High-throughput

0.536

High

1239230

FNDC5
Fibronectin type III domain-containing protein 5

1

7

High-throughput

0.536

High

1064050

TNIP1
TNFAIP3-interacting protein 1

2

3

High-throughput

0.533

High

1045276

THOC5
THO complex subunit 5 homolog

1

0

High-throughput

0.513

High

1071560

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.513

High

1299107

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

1299110

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

921152

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

4

High-throughput

0.489

High

1041439

CUL2
Cullin-2

1

5

High-throughput

0.489

High

1201377

MOGT3
2-acylglycerol O-acyltransferase 3

1

6

High-throughput

0.489

High

1299095

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.489

High

134171

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

Small-scale

0.479

High

338857

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

347629

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

374713

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

387327

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

427642

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

504599

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

542418

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

551809

DESP
Desmoplakin

1

3

High-throughput

0.479

High

553475

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

569973

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

683129

CASPE
Caspase-14

1

8

High-throughput

0.479

High

818366

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.479

High

832652

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

927420

1433Z
14-3-3 protein zeta/delta

1

3

Small-scale

0.479

High

959610

VIGLN
Vigilin

1

4

High-throughput

0.479

High

970830

DSG1
Desmoglein-1

1

1

High-throughput

0.479

High

1022176

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1035986

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1043170

CUL4A
Cullin-4A

1

5

High-throughput

0.479

High

1045995

PKP1
Plakophilin-1

1

4

High-throughput

0.479

High

1046137

DX39B
Spliceosome RNA helicase DDX39B

1

2

High-throughput

0.479

High

1046248

BLMH
Bleomycin hydrolase

1

2

High-throughput

0.479

High

1052740

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

10

High-throughput

0.479

High

1125341

FILA2
Filaggrin-2

1

9

High-throughput

0.479

High

1167534

SOSD1
Sclerostin domain-containing protein 1

1

1

Small-scale

0.479

High

1171299

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1200860

PAQR2
Adiponectin receptor protein 2

1

1

Small-scale

0.479

High

1206186

HORN
Hornerin

1

8

High-throughput

0.479

High

1281321

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.479

High

1299096

S10AE
Protein S100-A14

1

9

High-throughput

0.479

High

1299097

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1299098

ANLN
Anillin

1

2

High-throughput

0.479

High

1299103

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1299104

UBQL2
Ubiquilin-2

1

7

High-throughput

0.479

High

1299108

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.479

High

1299109

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

4

Small-scale

0.479

High

1080253

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.470

High

345128

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

396277

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

964951

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

993997

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

996002

DSC1
Desmocollin-1

1

0

High-throughput

0.458

High

1059803

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1134066

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1134402

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

1135391

ARM12
Armadillo repeat-containing protein 12

1

0

Small-scale

0.458

High

1287471

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.458

High

1299087

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1299089

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1299093

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1299094

AKTIP
AKT-interacting protein

1

0

Small-scale

0.458

High

1299102

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

1299111

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

853961

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.445

High

1044065

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.445

High

1130462

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1233153

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

170453

TIF1A
Transcription intermediary factor 1-alpha

1

4

Small-scale

0.437

High

282717

RNF8
E3 ubiquitin-protein ligase RNF8

1

4

High-throughput

0.437

High

325858

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.437

High

379748

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.437

High

651999

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

718117

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.437

High

721196

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

908980

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.437

High

1066551

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1116467

LARP7
La-related protein 7

1

1

High-throughput

0.437

High

1199671

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.437

High

1222527

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.437

High

1250990

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.437

High

1299088

FACD2
Fanconi anemia group D2 protein

1

12

High-throughput

0.437

High

1299090

DDX24
ATP-dependent RNA helicase DDX24

1

4

High-throughput

0.437

High

1299091

PRD14
PR domain zinc finger protein 14

1

7

Small-scale

0.437

High

1299092

RNF38
E3 ubiquitin-protein ligase RNF38

1

7

Small-scale

0.437

High

1299099

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1299101

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.437

High

1299105

TRI33
E3 ubiquitin-protein ligase TRIM33

1

3

High-throughput

0.437

High

572672

VGFR1
Vascular endothelial growth factor receptor 1

1

0

Small-scale

0.426

High

998157

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

1047215

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

150106

UTY
Histone demethylase UTY

1

0

High-throughput

0.279

Low

447989

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.279

Low

1293133

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

197375

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.249

Low

946594

DCD
Dermcidin

1

0

High-throughput

0.249

Low

1134462

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

1284376

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.249

Low

1299106

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.249

Low

1024266

IFT88
Intraflagellar transport protein 88 homolog

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024