Protein: ZC3H4
Zinc finger CCCH domain-containing protein 4

Gene: ZC3H4
Organism: Homo sapiens
Interactions: 155
UniProt ID: Q9UPT8

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1250060

WDR82
WD repeat-containing protein 82

4

17

Small-scale

0.886

High

478261

SNRPA
U1 small nuclear ribonucleoprotein A

1

11

High-throughput

0.691

High

576595

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

11

High-throughput

0.691

High

775376

FUS
RNA-binding protein FUS

1

9

High-throughput

0.691

High

1160345

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

13

High-throughput

0.691

High

1307534

RBM45
RNA-binding protein 45

1

16

High-throughput

0.691

High

1399794

RBM14
RNA-binding protein 14

1

13

High-throughput

0.691

High

1409877

RBM4B
RNA-binding protein 4B

1

17

High-throughput

0.691

High

1331478

ZFP41
Zinc finger protein 41 homolog

3

3

High-throughput

0.667

High

998112

CSK21
Casein kinase II subunit alpha

3

11

Small-scale

0.656

High

625705

CSK22
Casein kinase II subunit alpha'

3

11

High-throughput

0.650

High

995352

CSK2B
Casein kinase II subunit beta

3

2

Small-scale

0.633

High

1239693

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

2

High-throughput

0.628

High

473186

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.618

High

485517

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

9

High-throughput

0.618

High

1152678

ELAV1
ELAV-like protein 1

1

7

High-throughput

0.618

High

1369877

CELF1
CUGBP Elav-like family member 1

1

14

High-throughput

0.618

High

1387647

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

11

High-throughput

0.618

High

129561

MEN1
Menin

2

4

High-throughput

0.584

High

130658

SPT5H
Transcription elongation factor SPT5

2

9

High-throughput

0.584

High

373510

MYC
Myc proto-oncogene protein

2

13

High-throughput

0.584

High

558500

XRCC6
X-ray repair cross-complementing protein 6

2

2

High-throughput

0.584

High

1016671

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.575

High

1418645

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

17

High-throughput

0.575

High

1236120

CAN13
Calpain-13

2

2

High-throughput

0.574

High

1437409

LN28A
Protein lin-28 homolog A

2

10

High-throughput

0.552

High

191865

MAGB2
Melanoma-associated antigen B2

1

4

High-throughput

0.536

High

277438

TP4A3
Protein tyrosine phosphatase type IVA 3

1

3

High-throughput

0.536

High

457141

CAN1
Calpain-1 catalytic subunit

1

2

High-throughput

0.536

High

574518

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

600397

ZNF24
Zinc finger protein 24

1

2

High-throughput

0.536

High

824427

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

879765

MAPK2
MAP kinase-activated protein kinase 2

1

1

High-throughput

0.536

High

955761

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.536

High

1012281

RT11
Small ribosomal subunit protein uS11m

1

2

High-throughput

0.536

High

1065497

SSRP1
FACT complex subunit SSRP1

1

9

High-throughput

0.536

High

1142824

PEA15
Astrocytic phosphoprotein PEA-15

1

1

High-throughput

0.536

High

1253102

DBX2
Homeobox protein DBX2

1

15

High-throughput

0.536

High

1294355

ZN677
Zinc finger protein 677

1

2

High-throughput

0.536

High

1340480

DDX55
ATP-dependent RNA helicase DDX55

1

2

High-throughput

0.536

High

1351899

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.536

High

1368812

EZH1
Histone-lysine N-methyltransferase EZH1

1

16

High-throughput

0.536

High

1391859

AURKB
Aurora kinase B

1

4

High-throughput

0.536

High

1460676

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.536

High

1461782

TPX2
Targeting protein for Xklp2

1

2

High-throughput

0.536

High

1163293

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.515

High

542285

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

571011

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

933268

AIF1
Allograft inflammatory factor 1

1

0

High-throughput

0.513

High

943874

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

948614

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1023647

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1151438

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

0

High-throughput

0.493

High

1013356

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.489

High

1092838

MALL
MAL-like protein

1

3

High-throughput

0.489

High

1093786

GAGE5
G antigen 5

1

1

High-throughput

0.489

High

1196253

GAG2E
G antigen 2E

1

1

High-throughput

0.489

High

1449819

TM14B
Transmembrane protein 14B

1

2

High-throughput

0.489

High

1461599

ANR50
Ankyrin repeat domain-containing protein 50

1

5

High-throughput

0.489

High

1462578

BACE2
Beta-secretase 2

1

1

High-throughput

0.489

High

243304

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

260618

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

272553

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

346510

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

364033

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

406804

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

520458

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

590043

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

607227

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

636166

CD11B
Cyclin-dependent kinase 11B

1

5

High-throughput

0.479

High

674377

BRD2
Bromodomain-containing protein 2

1

15

High-throughput

0.479

High

696875

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

766015

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.479

High

786936

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.479

High

882949

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.479

High

905294

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

986818

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

995899

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

998949

H31
Histone H3.1

1

13

High-throughput

0.479

High

1067843

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

1089069

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

1097633

CBX3
Chromobox protein homolog 3

1

4

High-throughput

0.479

High

1108291

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1114672

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1138759

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1141366

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1155908

EZH2
Histone-lysine N-methyltransferase EZH2

1

16

High-throughput

0.479

High

1215899

RC3H1
Roquin-1

1

4

High-throughput

0.479

High

1256116

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1276976

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

11

High-throughput

0.479

High

1289727

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1290821

ZCH18
Zinc finger CCCH domain-containing protein 18

1

12

High-throughput

0.479

High

1311892

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.479

High

1313535

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1337852

CSK23
Casein kinase II subunit alpha 3

1

10

High-throughput

0.479

High

1338438

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1352838

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1364017

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

5

High-throughput

0.479

High

1364699

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1404840

RING2
E3 ubiquitin-protein ligase RING2

1

9

High-throughput

0.479

High

1407952

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1446441

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

1448790

RNC
Ribonuclease 3

1

9

High-throughput

0.479

High

1449251

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1452483

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1459330

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1460303

XPO7
Exportin-7

1

6

High-throughput

0.479

High

1461908

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

1462573

CD11A
Cyclin-dependent kinase 11A

1

5

High-throughput

0.479

High

1198225

PDCD4
Programmed cell death protein 4

1

0

High-throughput

0.458

High

1388457

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1429823

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1461309

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

328193

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.445

High

429060

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

649457

H1T
Histone H1t

1

6

High-throughput

0.445

High

686525

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.445

High

809921

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.445

High

861021

RS10
Small ribosomal subunit protein eS10

1

4

High-throughput

0.445

High

898887

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.445

High

977413

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.445

High

1034631

AK17A
A-kinase anchor protein 17A

1

5

High-throughput

0.445

High

1064046

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.445

High

1337437

SRFB1
Serum response factor-binding protein 1

1

1

High-throughput

0.445

High

1411911

UTP23
rRNA-processing protein UTP23 homolog

1

2

High-throughput

0.445

High

1461411

ZN346
Zinc finger protein 346

1

3

High-throughput

0.445

High

1461801

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.445

High

412820

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

1071200

ARL16
ADP-ribosylation factor-like protein 16

1

2

High-throughput

0.437

High

1250216

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.437

High

1452295

TBA8
Tubulin alpha-8 chain

1

2

High-throughput

0.437

High

1108418

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.426

High

1414019

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.426

High

1418932

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.426

High

1462577

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.426

High

1462579

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.426

High

667514

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.408

High

1462574

RT17
Small ribosomal subunit protein uS17m

1

2

High-throughput

0.407

High

1462575

RT02
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.407

High

1462576

RT18C
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.407

High

1431239

RSPH9
Radial spoke head protein 9 homolog

3

0

High-throughput

0.347

High

169220

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

317101

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.279

Low

376437

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

488089

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

488892

FURIN
Furin

1

0

High-throughput

0.279

Low

515914

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

1218130

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1314297

EFC13
EF-hand calcium-binding domain-containing protein 13

1

0

High-throughput

0.279

Low

1384737

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1388124

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1452960

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1012653

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.232

Low

1012790

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.232

Low

1364425

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025