Interactor 1: RFA1 (P22336)
Replication factor A protein 1 (RF-A protein 1) (DNA-binding protein BUF2) (Replication protein A 69 kDa DNA-binding subunit) (Single-stranded DNA-binding protein)
Gene: RFA1

Interactor 2: RFA2 (P26754)
Replication factor A protein 2 (RF-A protein 2) (DNA-binding protein BUF1) (Replication protein A 36 kDa subunit)
Gene: RFA2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 11805826, 18342608, 37140030, 24130504, 25499885, 11479296, 14634024, 16554755, 16429126, 28126821, 30065069, 30224481, 36056028, 37968396, 20190278, 21332387, 22354040
Identification Methods tandem affinity purification, two hybrid, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rep_fac-A_C~tRNA_anti-codon, REPA_OB_2~tRNA_anti-codon, tRNA_anti-codon~tRNA_anti-codon
Common GO terms GO:0000722 - telomere maintenance via recombination
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000794 - condensed nuclear chromosome
and 15 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 621
Sc

1 273
+ Hs
+ Hs
+ At
+ At
+ Os
+ Ca
+ Dm
+ Ce
+ Os

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Last updated: 11Aug2025