Interactor 1: WNT3A (P27467)
Protein Wnt-3a
Gene: WNT3A

Interactor 2: FZD8 (Q61091)
Frizzled-8 (Fz-8) (mFz8)
Gene: FZD8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 23791946, 18528331, 22575959, 31036956
Identification Methods bio-layer interferometry, anti tag coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fz~wnt
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0016055 - Wnt signaling pathway
GO:0035567 - non-canonical Wnt signaling pathway
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 352
Mm

1 685
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024