Protein: PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) (hGPCR43)

Gene: PIGO
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q8TEQ8

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0051377 - mannose-ethanolamine phosphotransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1353073

5HT3C
5-hydroxytryptamine receptor 3C

3

5

High-throughput

0.609

High

855363

5HT3A
5-hydroxytryptamine receptor 3A

3

5

High-throughput

0.604

High

1353075

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

2

0

High-throughput

0.602

High

1316334

AGRG5
Adhesion G-protein coupled receptor G5

2

5

High-throughput

0.601

High

1353074

LPAR1
Lysophosphatidic acid receptor 1

3

9

High-throughput

0.593

High

595085

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

0

High-throughput

0.576

High

1353091

SCN3B
Sodium channel regulatory subunit beta-3

1

2

High-throughput

0.575

High

1032630

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

1

High-throughput

0.574

High

1042765

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

9

High-throughput

0.558

High

1353082

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

5

High-throughput

0.549

High

132634

UPK1A
Uroplakin-1a

1

3

High-throughput

0.536

High

182686

GP182
G-protein coupled receptor 182

1

16

High-throughput

0.536

High

226343

SNG1
Synaptogyrin-1

1

1

High-throughput

0.536

High

374800

RASH
GTPase HRas

1

2

High-throughput

0.536

High

669039

FPR2
N-formyl peptide receptor 2

1

18

High-throughput

0.536

High

851186

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

878063

AGRE5
Adhesion G protein-coupled receptor E5

1

7

High-throughput

0.536

High

1154691

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.536

High

1185818

PTHD3
Patched domain-containing protein 3

1

2

High-throughput

0.536

High

1350016

SPP2B
Signal peptide peptidase-like 2B

1

4

High-throughput

0.536

High

1353078

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.536

High

1353086

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

317076

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.513

High

506977

POTEI
POTE ankyrin domain family member I

1

0

High-throughput

0.513

High

607397

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

0

High-throughput

0.513

High

789658

HPCL1
Hippocalcin-like protein 1

1

0

High-throughput

0.513

High

1353079

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

1353087

PCX3
Pecanex-like protein 3

1

0

High-throughput

0.513

High

1353092

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

422699

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

640430

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

12

High-throughput

0.489

High

733026

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

9

High-throughput

0.489

High

771189

APJ
Apelin receptor

1

10

High-throughput

0.489

High

771800

SCN4A
Sodium channel protein type 4 subunit alpha

1

1

High-throughput

0.489

High

835337

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

9

High-throughput

0.489

High

982106

RAP1A
Ras-related protein Rap-1A

1

1

High-throughput

0.489

High

1059321

NKG2E
NKG2-E type II integral membrane protein

1

6

High-throughput

0.489

High

1177848

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.489

High

1242881

S39A4
Zinc transporter ZIP4

1

9

High-throughput

0.489

High

1353076

T106A
Transmembrane protein 106A

1

4

High-throughput

0.489

High

1353084

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.489

High

951294

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

1353077

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

417621

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

1252148

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1353080

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.458

High

1353088

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.458

High

170890

CLGN
Calmegin

1

8

High-throughput

0.445

High

256093

S19A2
Thiamine transporter 1

1

2

High-throughput

0.445

High

351238

MOT3
Monocarboxylate transporter 3

1

4

High-throughput

0.445

High

869630

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

1

High-throughput

0.445

High

1093553

TRDN
Triadin

1

1

High-throughput

0.445

High

1131580

MFS10
Major facilitator superfamily domain-containing protein 10

1

4

High-throughput

0.445

High

1218847

GP107
Protein GPR107

1

3

High-throughput

0.445

High

1236243

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.445

High

1242181

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

1335642

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.445

High

1348027

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

5

High-throughput

0.445

High

218529

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

1005545

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

3

High-throughput

0.437

High

1254784

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1353090

T106B
Transmembrane protein 106B

1

4

High-throughput

0.437

High

1175883

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.426

High

1353072

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.426

High

1353085

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

303262

S22A5
Organic cation/carnitine transporter 2

1

3

High-throughput

0.407

High

732935

GASR
Gastrin/cholecystokinin type B receptor

1

1

High-throughput

0.407

High

886110

CXCR3
C-X-C chemokine receptor type 3

1

16

High-throughput

0.407

High

956953

CXCR4
C-X-C chemokine receptor type 4

1

18

High-throughput

0.407

High

1337879

ZNT7
Zinc transporter 7

1

5

High-throughput

0.407

High

1353081

S1PR3
Sphingosine 1-phosphate receptor 3

1

8

High-throughput

0.407

High

1353089

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.407

High

931417

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

0

High-throughput

0.347

High

1195451

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

1308504

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1316793

SELH
Selenoprotein H

1

0

High-throughput

0.279

Low

1328487

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.279

Low

1333577

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1339944

OR4N2
Olfactory receptor 4N2

1

0

High-throughput

0.279

Low

1108513

NAR3
Ecto-ADP-ribosyltransferase 3

1

0

High-throughput

0.249

Low

1351216

MCLN3
Mucolipin-3

1

0

High-throughput

0.249

Low

1353083

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

222308

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low

1308777

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025