HitPredict

Interactor 1: NSR1 (P27476)
Nuclear localization sequence-binding protein (p67)
Gene: NSR1

Interactor 2: MRD1 (Q06106)
Multiple RNA-binding domain-containing protein 1
Gene: MRD1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0032040 - small-subunit processome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 414 Sc			1 887
+	Hs
		1288653 PABP5_HUMAN (172-359): 3.98e-34: 132: 23.40		RBM19_HUMAN (1-886): 3.37e-82: 286: 22.67
+	Sc
		376663 NSR1_YEAST (1-414): 1.23e-61: 206: 100.00		PABP_YEAST (2-343): 1.25e-20: 99.1: 12.57
+	Hs
		1020249 ELAV2_HUMAN (62-249): 2.09e-24: 105: 14.89		PABP4_HUMAN (1-669): 8.45e-44: 171: 11.10
+	Hs
		516495 PABP4_HUMAN (7-261): 4.85e-44: 164: 15.95		PABP1_HUMAN (2-327): 1.99e-24: 111: 13.64
+	Sc
		648344 NSR1_YEAST (1-414): 1.23e-61: 206: 100.00		NSR1_YEAST (664-838): 2.53e-11: 68.6: 28.33
+	Hs
		474021 PABP4_HUMAN (7-261): 4.85e-44: 164: 15.95		PAB4L_HUMAN (2-204): 2.45e-17: 86.8: 18.36
+	Hs
		516635 PABP5_HUMAN (172-359): 3.98e-34: 132: 23.40		PABP1_HUMAN (2-327): 1.99e-24: 111: 13.64
+	Zm
		8143 A0A1D6ELH4_MAIZE (135-355): 5.96e-41: 155: 23.08		A0A1D6ELH4_MAIZE (2-254): 2.45e-16: 85.6: 11.86
+	Hs
		1119141 PAP1L_HUMAN (169-356): 9.91e-47: 171: 23.94		PABP5_HUMAN (3-207): 5.79e-11: 67.5: 10.63
+	Hs
		474034 PAB4L_HUMAN (2-247): 5.9e-43: 156: 13.71		PABP5_HUMAN (3-207): 5.79e-11: 67.5: 10.63
+	Hs
		516484 ELAV2_HUMAN (62-249): 2.09e-24: 105: 14.89		PABP1_HUMAN (2-327): 1.99e-24: 111: 13.64
+	Hs
		474019 ELAV2_HUMAN (62-249): 2.09e-24: 105: 14.89		PAB4L_HUMAN (2-204): 2.45e-17: 86.8: 18.36
+	Hs
		516471 TIAR_HUMAN (259-356): 6.05e-14: 74.9: 23.47		PABP1_HUMAN (2-327): 1.99e-24: 111: 13.64
+	Mm
		665745 TIA1_MOUSE (261-356): 9.28e-14: 74.1: 22.92		PABP1_MOUSE (2-327): 1.65e-24: 111: 13.94
+	Sc
		376562 PABP_YEAST (264-356): 8.86e-15: 78: 25.81		PABP_YEAST (2-343): 1.25e-20: 99.1: 12.57
+	Hs
		1020306 ELAV2_HUMAN (62-249): 2.09e-24: 105: 14.89		PABP5_HUMAN (3-207): 5.79e-11: 67.5: 10.63