HitPredict

Interactor 1: TNR5 (P27512)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CD antigen CD40)
Gene: Cd40

Interactor 2: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 18635759, 10748240, 25072696, 23334419, 17878362, 17919601
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002637 - regulation of immunoglobulin production
GO:0031625 - ubiquitin protein ligase binding
GO:0035631 - CD40 receptor complex
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 289
Mm

1 501
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024