Interactor 1: ARNT (P27540)
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Gene: ARNT

Interactor 2: NPAS2 (Q99743)
Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Basic-helix-loop-helix-PAS protein MOP4) (Class E basic helix-loop-helix protein 9) (bHLHe9) (Member of PAS protein 4) (PAS domain-containing protein 4)
Gene: NPAS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 9576906
Identification Methods two hybrid, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH, HLH~PAS, PAS~PAS, PAS~PAS_11, PAS_11~PAS_11
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 789
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Last updated: 15 Jul 2024