HitPredict

Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	22177115, 22199229, 22922743, 21179020
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Histone~Sin3_corepress
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1536 Sc			1 136
+	Hs
		998714 SIN3A_HUMAN (109-525): 1.24e-62: 237: 33.64		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		1017144 SIN3A_HUMAN (109-525): 1.24e-62: 237: 33.64		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		1162010 SIN3A_HUMAN (109-525): 1.24e-62: 237: 33.64		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Hs
		274306 SIN3B_HUMAN (185-472): 5.88e-24: 112: 18.81		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		274336 SIN3B_HUMAN (185-472): 5.88e-24: 112: 18.81		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03