HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	20936779
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1229 Hs			1 2843
+	Hs
		626225 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626277 YM012_HUMAN (510-1065): 5.13e-28: 122: 14.72		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		554267 MUC1_HUMAN (47-509): 1.16e-20: 100: 11.64		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		72711 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626063 NU214_HUMAN (91-936): 1.02e-10: 68.8: 10.61		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626080 NUP98_HUMAN (784-1215): 1.89e-09: 64.3: 20.76		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		1303336 MUC4_HUMAN (50-1220): 3.41e-48: 191: 13.03		MUC4_HUMAN (710-2820): 1.56e-75: 284: 9.45
+	Hs
		257652 ANKH1_HUMAN (453-1171): 3.1e-11: 70.5: 15.06		ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08
+	Hs
		1302939 MINT_HUMAN (1-1187): 3.89e-14: 80.1: 9.85		NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41
+	Hs
		1057810 NCOA6_HUMAN (359-1228): 9.06e-13: 75.3: 9.95		NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41
+	Hs
		1056827 MDC1_HUMAN (80-893): 2.1e-29: 129: 10.92		MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74
+	Dm
		113976 M9PB30_DROME (3-712): 4.66e-23: 109: 9.00		M9PB30_DROME (1208-2013): 4.08e-21: 104: 9.83
+	Hs
		820951 POZP3_HUMAN (243-348): 3.32e-26: 109: 76.64		PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24
+	Hs
		1056876 MDC1_HUMAN (80-893): 2.1e-29: 129: 10.92		MICA3_HUMAN (1200-1800): 2.91e-09: 65.2: 13.62
+	Hs
		1056898 ARI1B_HUMAN (129-1213): 3.55e-15: 83.3: 9.44		MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74
+	Hs
		554259 MUC1_HUMAN (47-509): 1.16e-20: 100: 11.64		MUC1_HUMAN (733-1434): 9.86e-12: 73.4: 9.40
+	Hs
		820969 ANKH1_HUMAN (453-1171): 3.1e-11: 70.5: 15.06		PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24
+	Mm
		1207212 NCOA6_MOUSE (339-1229): 3.74e-12: 73.3: 7.33		KMT2C_MOUSE (727-2826): 5.47e-17: 90.9: 7.58
+	Hs
		1057773 NCOA6_HUMAN (359-1228): 9.06e-13: 75.3: 9.95		KMT2C_HUMAN (2340-2838): 4.14e-09: 64.9: 8.02
+	Mm
		1351630 PCLO_MOUSE (2-1158): 3.65e-09: 63.7: 7.80		PCLO_MOUSE (810-2544): 4.79e-12: 74.5: 9.79