HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RFC5 (P40937)
Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)
Gene: RFC5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26474068, 24981860, 37827155, 24332808
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication GO:0006261 - DNA-templated DNA replication GO:0006281 - DNA repair
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 340
+	Hs
		650501 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC4_HUMAN (1-331): 9.47e-89: 272: 36.77
+	Hs
		650502 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC2_HUMAN (2-331): 2.97e-86: 265: 35.35
+	Hs
		650558 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC3_HUMAN (21-340): 6.47e-62: 202: 24.00