HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 1590
+	Hs
		650711 RFA1_HUMAN (1-616): 0: 781: 100.00		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		229317 RFA1_HUMAN (1-616): 0: 781: 100.00		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		650435 RFA1_HUMAN (1-616): 0: 781: 100.00		SMCA1_HUMAN (618-1559): 0: 797: 28.00
+	Hs
		651222 RFA1_HUMAN (1-616): 0: 781: 100.00		CHD4_HUMAN (370-1589): 0: 749: 22.31
+	Hs
		652312 RFA1_HUMAN (1-616): 0: 781: 100.00		CHD8_HUMAN (19-1359): 0: 741: 21.67
+	Sc
		607354 RFA1_YEAST (4-615): 0: 596: 31.69		ISW2_YEAST (537-1576): 0: 765: 24.75
+	Sc
		607262 RFA1_YEAST (4-615): 0: 596: 31.69		ISW1_YEAST (608-1588): 0: 726: 26.73
+	Sc
		603276 RFA1_YEAST (4-615): 0: 596: 31.69		SNF2_YEAST (1189-1553): 2.56e-26: 120: 16.16
+	Sc
		607235 RFA1_YEAST (4-615): 0: 596: 31.69		STH1_YEAST (1216-1505): 1.4e-19: 98.2: 14.33