Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.671

The method score is based on:

Property Details
Experiments 10608806, 26212458, 18162465, 24332808
Identification Methods unspecified method, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006281 - DNA repair
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 616
Hs

1 2644
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024