HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 1214
+	Hs
		232009 RFA1_HUMAN (1-616): 0: 781: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Sc
		607297 RFA1_YEAST (4-615): 0: 596: 31.69		RSC8_YEAST (336-751): 4.61e-104: 342: 28.30
+	Sc
		607234 RFA1_YEAST (4-615): 0: 596: 31.69		SWI3_YEAST (254-793): 1.23e-96: 329: 26.48
+	Hs
		652734 RFA1_HUMAN (1-616): 0: 781: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Mm
		1169762 RFA1_MOUSE (1-614): 0: 745: 83.95		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		261410 RFA1_HUMAN (1-616): 0: 781: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		652232 RFA1_HUMAN (1-616): 0: 781: 100.00		PTN23_HUMAN (768-1213): 4.36e-30: 132: 19.59
+	Hs
		652459 RFA1_HUMAN (1-616): 0: 781: 100.00		OGFR_HUMAN (804-1190): 3.3e-13: 76.2: 16.02
+	Hs
		650764 RFA1_HUMAN (1-616): 0: 781: 100.00		SC24C_HUMAN (1005-1213): 5.27e-13: 75.8: 19.28
+	Hs
		651725 RFA1_HUMAN (1-616): 0: 781: 100.00		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57