HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: FANCJ (Q9BX63)
Fanconi anemia group J protein (EC 3.6.4.12) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)
Gene: BRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	17596542, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology, far western blotting, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006289 - nucleotide-excision repair GO:0046872 - metal ion binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 1249
+	Hs
		574126 RFA1_HUMAN (1-616): 0: 781: 100.00		ERCC2_HUMAN (212-902): 0: 668: 23.12
+	Hs
		652450 RFA1_HUMAN (1-616): 0: 781: 100.00		RTEL1_HUMAN (10-260): 2.1e-53: 207: 20.72