HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006310 - DNA recombination
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 463
+	Hs
		652640 RFA1_HUMAN (1-616): 0: 781: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Sc
		607368 RFA1_YEAST (4-615): 0: 596: 31.69		RUVB2_YEAST (7-451): 0: 650: 68.76
+	Sc
		607333 RFA1_YEAST (4-615): 0: 596: 31.69		RUVB1_YEAST (12-451): 0: 605: 41.72