HitPredict

Interactor 1: CD82 (P27701)
CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
Gene: CD82

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9862348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 267 Hs			1 236
+	Hs
		887767 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		653088 CD82_HUMAN (1-267): 5.82e-73: 225: 100.00		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		602222 CD82_HUMAN (1-267): 5.82e-73: 225: 100.00		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		887904 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		446012 CD82_HUMAN (1-267): 5.82e-73: 225: 100.00		CD63_HUMAN (1-232): 2.98e-52: 170: 22.95
+	Hs
		819444 CD151_HUMAN (3-261): 2.39e-58: 188: 27.48		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		583861 CD82_HUMAN (1-267): 5.82e-73: 225: 100.00		CD53_HUMAN (1-234): 4.26e-47: 157: 29.06
+	Hs
		819445 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		279369 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		TSN9_HUMAN (5-233): 7.12e-53: 172: 26.05
+	Hs
		602239 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		819462 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		905534 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		TSN14_HUMAN (11-230): 6.42e-52: 170: 21.65
+	Hs
		602271 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		602230 CD151_HUMAN (3-261): 2.39e-58: 188: 27.48		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		326051 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326141 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		237719 CD151_HUMAN (3-261): 2.39e-58: 188: 27.48		TSN2_HUMAN (3-234): 1.88e-44: 150: 39.22
+	Hs
		326042 CD151_HUMAN (3-261): 2.39e-58: 188: 27.48		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48