HitPredict

Interactor 1: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Interactor 2: PDK2 (Q15119)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)
Gene: PDK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 28514442, 33961781, 36836934
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0042803 - protein homodimerization activity
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 423
Hs

1 407
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025