HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: TM11B (Q86T26)
Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5)
Gene: TMPRSS11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	28514442, 33961781, 34709727
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 416
+	Hs
		161100 CLGN_HUMAN (11-546): 0: 652: 59.85		TM11B_HUMAN (1-416): 0: 516: 100.00
+	Hs
		654214 CALX_HUMAN (1-592): 0: 786: 100.00		TMPS3_HUMAN (158-414): 6.93e-107: 324: 38.08
+	Hs
		409498 CALX_HUMAN (1-592): 0: 786: 100.00		HEPS_HUMAN (157-415): 4.97e-105: 318: 37.27
+	Hs
		160971 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS2_HUMAN (70-414): 1.17e-106: 325: 28.94
+	Hs
		161157 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS4_HUMAN (143-413): 4.83e-103: 314: 34.93
+	Hs
		161146 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS5_HUMAN (158-415): 3.68e-101: 309: 35.99
+	Hs
		654948 CALX_HUMAN (1-592): 0: 786: 100.00		TEST_HUMAN (171-410): 9.23e-51: 175: 39.92
+	Hs
		653645 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		TM11B_HUMAN (1-416): 0: 516: 100.00
+	Hs
		177824 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		TMPS2_HUMAN (70-414): 1.17e-106: 325: 28.94