HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 832
+	Hs
		655466 P85A_HUMAN (1-724): 0: 596: 100.00		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		883587 P55G_HUMAN (271-723): 1.4e-104: 329: 72.31		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		1267436 P55G_HUMAN (271-723): 1.4e-104: 329: 72.31		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Mm
		103593 P85A_MOUSE (1-724): 0: 592: 95.99		ANK3_MOUSE (659-832): 7.13e-44: 174: 33.14
+	Hs
		1021414 RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		1021423 RHG22_HUMAN (106-573): 8.83e-56: 204: 14.05		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		856146 CHIO_HUMAN (129-305): 2.17e-54: 195: 23.76		ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47
+	Hs
		551050 CHIN_HUMAN (588-696): 4.99e-12: 70.8: 18.18		ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47
+	Dm
		113921 M9PAY7_DROME (322-428): 1.98e-13: 71.4: 27.78		ANKHM_DROME (396-574): 1.03e-24: 113: 17.03