HitPredict

Interactor 1: TBAL3 (A6NHL2)
Tubulin alpha chain-like 3 (EC 3.6.5.-)
Gene: TUBAL3

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Tubulin, Cpn60_TCP1~Tubulin_C
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Hs			1 543
+	Hs
		65560 TBAL3_HUMAN (1-446): 0: 947: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		65558 TBAL3_HUMAN (1-446): 0: 947: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		65553 TBAL3_HUMAN (1-446): 0: 947: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Mm
		997239 TBA1A_MOUSE (1-443): 0: 690: 73.82		TCPH_MOUSE (1-543): 0: 656: 95.96
+	Hs
		1407535 TBA1C_HUMAN (1-444): 0: 692: 73.20		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		996823 TBA1B_HUMAN (1-443): 0: 692: 74.04		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		881872 TBA1B_HUMAN (1-443): 0: 692: 74.04		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882121 TBA1C_HUMAN (1-444): 0: 692: 73.20		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		881999 TBA1A_HUMAN (1-443): 0: 690: 73.82		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		875911 TBA1B_HUMAN (1-443): 0: 692: 74.04		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		876148 TBA1C_HUMAN (1-444): 0: 692: 73.20		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		876035 TBA1A_HUMAN (1-443): 0: 690: 73.82		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610613 TBA1B_HUMAN (1-443): 0: 692: 74.04		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610857 TBA1C_HUMAN (1-444): 0: 692: 73.20		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		65561 TBAL3_HUMAN (1-446): 0: 947: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		610736 TBA1A_HUMAN (1-443): 0: 690: 73.82		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899340 TBA1B_HUMAN (1-443): 0: 692: 74.04		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899555 TBA1C_HUMAN (1-444): 0: 692: 73.20		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Mm
		997240 TBA1A_MOUSE (1-443): 0: 690: 73.82		TCPD_MOUSE (24-520): 1.63e-90: 289: 34.38
+	Hs
		899449 TBA1A_HUMAN (1-443): 0: 690: 73.82		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79