HitPredict

Interactor 1: PSB9 (P28065)
Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)
Gene: PSMB9

Interactor 2: ECM29 (Q5VYK3)
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
Gene: ECPAS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 1845
+	Hs
		656251 PSA5_HUMAN (5-219): 2.62e-78: 236: 17.90		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		656731 PSB5_HUMAN (2-219): 2.03e-73: 224: 27.15		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		1139426 PSB7_HUMAN (10-205): 6.35e-72: 221: 27.04		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		637703 PSA2_HUMAN (6-217): 4.83e-72: 220: 14.48		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		638148 PSA4_HUMAN (5-217): 2.38e-71: 219: 15.49		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Sc
		751158 PSB1_YEAST (13-212): 1.62e-76: 231: 45.27		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		675414 PSB5_YEAST (16-205): 1.55e-72: 223: 29.69		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		625930 PSB2_YEAST (11-219): 6.1e-72: 221: 27.27		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Hs
		656268 PSA5_HUMAN (5-219): 2.62e-78: 236: 17.90		CAND1_HUMAN (282-1301): 2.08e-34: 146: 12.77
+	Hs
		637714 PSA2_HUMAN (6-217): 4.83e-72: 220: 14.48		CAND1_HUMAN (282-1301): 2.08e-34: 146: 12.77