HitPredict

Interactor 1: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3)
Gene: PSMB4

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)
Gene: PSMB7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.946

The method score is based on:

Property Details
Experiments 33961781, 34349018, 26186194, 28514442, 37071682, 17948026
Identification Methods affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 264
Hs

1 277
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+ Ce
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+ Af
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024