HitPredict

Interactor 1: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3)
Gene: PSMB4

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

Property	Details
Experiments	26186194, 28514442, 33961781, 17948026, 17189198
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 264 Hs			1 141
+	Hs
		656342 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		156378 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656085 PSB8_HUMAN (14-254): 2.23e-75: 232: 23.29		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637759 PSA2_HUMAN (28-258): 1.95e-74: 228: 14.23		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		893773 PSA6_HUMAN (26-261): 3.03e-74: 228: 11.69		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1152327 Q6IBT1_HUMAN (47-253): 1.89e-70: 219: 17.87		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1303498 PSB7_HUMAN (51-253): 3.22e-70: 219: 18.23		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656796 PSB5_HUMAN (11-252): 1.96e-70: 218: 21.07		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		594663 PSB1_HUMAN (26-246): 7.33e-70: 217: 22.61		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		771482 PSB10_HUMAN (35-253): 4.83e-67: 210: 19.18		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1367985 PSB4_DROME (11-263): 3.53e-75: 231: 39.54		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1278643 PSA5_DROME (26-255): 4.47e-75: 230: 14.23		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1178961 Q7K148_DROME (50-242): 4.09e-74: 229: 25.91		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367991 Q9VUJ1_DROME (56-264): 4.4e-70: 218: 16.27		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367996 Q9W470_DROME (47-253): 9.92e-68: 213: 19.32		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50