HitPredict

Interactor 1: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Interactor 2: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 14733938, 17948026, 28514442, 28292943, 33961781, 34349018
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 263
Hs

1 205
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024