HitPredict

Interactor 1: TBP2 (P28148)
TATA-box-binding protein 2 (TATA sequence-binding protein 2) (AtTBP2) (TBP-2) (TATA-binding factor 2) (TATA-box factor 2) (Transcription initiation factor TFIID TBP-2 subunit)
Gene: TBP2

Interactor 2: TAF1 (Q8LRK9)
Transcription initiation factor TFIID subunit 1 (TAFII250-A) (TBP-associated factor 1) (AtTAF1) (Transcription initiation factor TFIID subunit 1-A)
Gene: TAF1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	17340043
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	DUF3591~TBP, TBP~TBP-binding
Common GO terms	GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0017025 - TBP-class protein binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 200 At			1 1919
+	At
		656809 TBP1_ARATH (1-200): 7.66e-106: 303: 93.50		TAF1_ARATH (1-1919): 0: 2147: 100.00
+	Sc
		527022 TBP_YEAST (2-198): 9.19e-97: 282: 77.89		TAF1_YEAST (756-1327): 4.44e-163: 530: 20.24
+	Sp
		571842 TBP_SCHPO (3-197): 3.81e-98: 285: 80.00		T111_SCHPO (759-1326): 6.75e-154: 502: 20.89
+	Hs
		589901 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		CBP_HUMAN (1352-1909): 1.94e-73: 275: 14.76
+	Hs
		589939 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		TRI33_HUMAN (1178-1919): 7.6e-67: 250: 12.78
+	Mm
		661500 TBP_MOUSE (9-197): 3.96e-97: 286: 79.89		SMCA4_MOUSE (1648-1886): 2.05e-40: 166: 19.76
+	Dm
		589958 TBP_DROME (11-197): 1.27e-98: 291: 78.08		TAF1_DROME (1487-1915): 2.54e-37: 157: 13.83
+	Hs
		589810 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		SMCA2_HUMAN (1625-1886): 3.8e-38: 159: 22.26
+	Sc
		526993 TBP_YEAST (2-198): 9.19e-97: 282: 77.89		BDF1_YEAST (1514-1905): 8.12e-39: 158: 12.65
+	Hs
		589777 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		TAF1_HUMAN (1583-1915): 1.86e-33: 144: 17.49
+	Hs
		589893 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		TAF1L_HUMAN (1583-1915): 5.02e-33: 142: 17.20
+	Sc
		527049 TBP_YEAST (2-198): 9.19e-97: 282: 77.89		GCN5_YEAST (1735-1906): 1.8e-35: 143: 24.14
+	Hs
		589782 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		BRD2_HUMAN (1759-1911): 1.73e-25: 116: 18.71
+	Sc
		526989 TBP_YEAST (2-198): 9.19e-97: 282: 77.89		SPT7_YEAST (1779-1916): 4.3e-23: 109: 24.65
+	Hs
		600118 TBPL1_HUMAN (15-197): 1.38e-69: 211: 39.34		TAF1_HUMAN (1583-1915): 1.86e-33: 144: 17.49
+	Hs
		589845 TBP_HUMAN (9-197): 5.91e-97: 286: 79.89		EP300_HUMAN (1050-1832): 3.56e-10: 67.7: 8.42
+	Hs
		913427 TBPL1_HUMAN (15-197): 1.38e-69: 211: 39.34		TAF1L_HUMAN (1583-1915): 5.02e-33: 142: 17.20