HitPredict

Interactor 1: PTP1 (P28191)
Tyrosine-protein phosphatase 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1)
Gene: ptp-1

Interactor 2: GLR1 (P34299)
Glutamate receptor 1
Gene: glr-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	30417267
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1026 Ce			1 962
+	Rn
		585158 E41L1_RAT (4-757): 9.18e-136: 432: 23.62		GRIA1_RAT (10-949): 0: 748: 34.52
+	Rn
		585225 E41L1_RAT (4-757): 9.18e-136: 432: 23.62		GRIA4_RAT (11-936): 0: 738: 34.69
+	Hs
		786708 E41L1_HUMAN (4-757): 1.21e-129: 416: 23.42		GRIA1_HUMAN (10-949): 0: 751: 34.03
+	Hs
		505583 EPB41_HUMAN (4-589): 4.81e-134: 427: 24.67		GRIA4_HUMAN (11-936): 0: 739: 34.69
+	Hs
		816228 E41L3_HUMAN (24-773): 6.4e-131: 425: 22.56		GRIA4_HUMAN (11-936): 0: 739: 34.69
+	Hs
		204626 E41L2_HUMAN (23-714): 2.14e-126: 411: 22.71		GRIA1_HUMAN (10-949): 0: 751: 34.03
+	Hs
		816225 E41L1_HUMAN (4-757): 1.21e-129: 416: 23.42		GRIA4_HUMAN (11-936): 0: 739: 34.69
+	Hs
		616949 PTPRD_HUMAN (322-1012): 8.35e-118: 401: 19.84		GRIK1_HUMAN (8-885): 0: 740: 29.09
+	Mm
		963780 E41L3_MOUSE (24-770): 2.04e-132: 425: 22.07		NMDE2_MOUSE (3-941): 0: 581: 18.70
+	Hs
		1020091 PTPRJ_HUMAN (341-1016): 2.61e-130: 429: 19.89		NMDE2_HUMAN (3-955): 0: 574: 18.20
+	Mm
		719298 PTN11_MOUSE (663-1022): 1.38e-129: 407: 30.28		NMDE2_MOUSE (3-941): 0: 581: 18.70
+	Mm
		69650 PTPRS_MOUSE (291-1012): 1.78e-118: 403: 18.24		GRID2_MOUSE (4-940): 0: 577: 21.83
+	Hs
		663977 PTN4_HUMAN (6-516): 3.33e-113: 373: 31.20		NMDE1_HUMAN (2-956): 0: 581: 16.88
+	Hs
		203180 PTN4_HUMAN (6-516): 3.33e-113: 373: 31.20		GRID2_HUMAN (4-940): 0: 574: 21.73
+	Mm
		1142979 PTN4_MOUSE (6-516): 2.52e-111: 368: 31.01		GRID2_MOUSE (4-940): 0: 577: 21.83
+	Hs
		441195 PTPRC_HUMAN (514-1026): 2.62e-80: 288: 15.61		NMDE2_HUMAN (3-955): 0: 574: 18.20
+	Hs
		1060436 PTPRK_HUMAN (419-1015): 3.29e-65: 242: 17.01		NMDE3_HUMAN (5-959): 0: 580: 18.86
+	Hs
		617106 PTPRG_HUMAN (405-1026): 4.91e-64: 239: 13.81		NMDE2_HUMAN (3-955): 0: 574: 18.20
+	Rn
		723631 Q66HJ7_RAT (371-1012): 4.41e-117: 380: 18.28		NMDZ1_RAT (394-888): 9.06e-56: 211: 31.18
+	Hs
		984265 PTPRK_HUMAN (419-1015): 3.29e-65: 242: 17.01		NMDZ1_HUMAN (394-909): 7.41e-56: 211: 30.74