HitPredict

Interactor 1: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	28298427, 12006486
Identification Methods	two hybrid, pull down, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 458 Hs			1 197
+	Hs
		658229 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		158261 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		658221 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		658227 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Rn
		223210 5HT2C_RAT (1-458): 1.11e-107: 328: 88.04		MPDZ_RAT (22-175): 2.93e-15: 75.2: 19.87
+	Hs
		280022 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		MPDZ_HUMAN (39-162): 6.77e-13: 68.6: 20.16
+	Hs
		626685 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		159159 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		626684 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		626686 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90
+	Hs
		656994 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		656997 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		600726 DRD1_HUMAN (70-385): 2.99e-83: 265: 27.88		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		428993 ADRB2_HUMAN (22-457): 4.42e-78: 250: 23.70		SYJ2B_HUMAN (90-188): 8.25e-31: 111: 34.62
+	Hs
		626682 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Rn
		495779 ADRB2_RAT (19-438): 1.92e-78: 251: 24.18		DLG4_RAT (59-195): 2.17e-23: 98.7: 26.76
+	Hs
		280021 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		MPDZ_HUMAN (39-162): 6.77e-13: 68.6: 20.16
+	Hs
		626691 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		626693 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		GOPC_HUMAN (92-173): 2.58e-13: 69.3: 46.34
+	Hs
		429106 ADRB2_HUMAN (22-457): 4.42e-78: 250: 23.70		SNX27_HUMAN (91-175): 2.59e-12: 66.6: 38.14