Protein: AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)

Gene: AL7A1, ALDH7A1
Organism: Homo sapiens
Interactions: 144
UniProt ID: P49419

Gene Ontology (top 5):
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0004043 - L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

827769

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

2

13

High-throughput

0.783

High

827788

XRCC4
DNA repair protein XRCC4

3

0

High-throughput

0.638

High

827785

EPS8
Epidermal growth factor receptor kinase substrate 8

2

0

Small-scale

0.605

High

827833

ERP44
Endoplasmic reticulum resident protein 44

2

1

High-throughput

0.601

High

827780

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.580

High

725388

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.536

High

827774

COPA
Coatomer subunit alpha

1

6

High-throughput

0.536

High

827778

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.536

High

827804

LDH6A
L-lactate dehydrogenase A-like 6A

1

1

High-throughput

0.536

High

827818

MK15
Mitogen-activated protein kinase 15

1

1

High-throughput

0.536

High

827840

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.536

High

827791

EMC2
ER membrane protein complex subunit 2

2

4

High-throughput

0.521

High

393100

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.515

High

726082

BASI
Basigin

1

3

High-throughput

0.515

High

116796

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

149580

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

313234

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.513

High

336413

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

471566

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

827820

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

827831

SIKE1
Suppressor of IKBKE 1

1

0

High-throughput

0.513

High

174713

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

394329

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

827814

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.493

High

827846

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

827836

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.489

High

226842

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

262756

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

294528

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

346223

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

440414

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

5

High-throughput

0.479

High

455210

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

552213

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

650651

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

827777

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

827787

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

5

High-throughput

0.479

High

827789

CUL4A
Cullin-4A

1

4

High-throughput

0.479

High

827794

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

827799

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

827815

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

827822

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

827823

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.479

High

827830

BAG1
BAG family molecular chaperone regulator 1

1

2

High-throughput

0.479

High

827839

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

4

High-throughput

0.479

High

827856

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

827859

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

338122

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

503676

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

717556

BMI1
Polycomb complex protein BMI-1

1

0

Small-scale

0.458

High

827848

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.458

High

295507

RECQ5
ATP-dependent DNA helicase Q5

1

2

High-throughput

0.457

High

48294

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

264282

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.445

High

335382

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.445

High

401634

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

496559

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

501829

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

653519

CALR
Calreticulin

1

2

High-throughput

0.445

High

654168

CALX
Calnexin

1

2

High-throughput

0.445

High

821934

KC1A
Casein kinase I isoform alpha

1

1

High-throughput

0.445

High

827779

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.445

High

827782

ARF5
ADP-ribosylation factor 5

1

2

High-throughput

0.445

High

827801

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

827805

NBEL2
Neurobeachin-like protein 2

1

3

High-throughput

0.445

High

827807

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.445

High

827808

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

827811

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.445

High

827819

SCFD1
Sec1 family domain-containing protein 1

1

1

High-throughput

0.445

High

827827

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

827837

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.445

High

827841

RGAP1
Rac GTPase-activating protein 1

1

1

High-throughput

0.445

High

827857

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

827858

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

827863

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

719954

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

827802

RC3H1
Roquin-1

1

1

Small-scale

0.437

High

827806

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

827844

Q9H4D1
Protein kinase

1

3

High-throughput

0.437

High

827845

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

827847

RC3H2
Roquin-2

1

1

Small-scale

0.437

High

58055

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

199296

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

200989

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

277026

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

297729

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.426

High

432599

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

532079

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

818894

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

827771

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

827772

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

827773

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

827776

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

827781

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

827786

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

827790

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

827792

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

827793

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

827797

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

827803

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

827812

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

827813

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

827825

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

827829

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

827842

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

827852

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.426

High

827853

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.426

High

827855

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

827862

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

50112

HACL2
2-hydroxyacyl-CoA lyase 2

1

3

High-throughput

0.407

High

99775

F5H6I7
Atlastin GTPase 3

1

3

High-throughput

0.407

High

258908

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

306997

RTN3
Reticulon-3

1

2

High-throughput

0.407

High

310551

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.407

High

827770

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

827775

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

827796

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.407

High

827798

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

2

High-throughput

0.407

High

827800

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.407

High

827816

ATLA2
Atlastin-2

1

3

High-throughput

0.407

High

827821

ATLA1
Atlastin-1

1

3

High-throughput

0.407

High

827834

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.407

High

827838

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.407

High

827843

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.407

High

827850

RTN4
Reticulon-4

1

2

High-throughput

0.407

High

827860

DHRS7
Dehydrogenase/reductase SDR family member 7

1

2

High-throughput

0.407

High

827861

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

827826

T3HPD
Trans-3-hydroxy-L-proline dehydratase

2

0

High-throughput

0.318

High

827810

EMC1
ER membrane protein complex subunit 1

2

0

High-throughput

0.298

High

827828

PKNX2
Homeobox protein PKNOX2

1

0

High-throughput

0.279

Low

344954

CYTN
Cystatin-SN

1

0

Small-scale

0.249

Low

827784

CAC1B
Voltage-dependent N-type calcium channel subunit alpha-1B

1

0

High-throughput

0.249

Low

202841

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.232

Low

266125

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

827783

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

827795

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

827809

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

827817

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

827824

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.232

Low

827832

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

827835

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

827849

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

827851

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

827854

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024