HitPredict

Interactor 1: SMCA1 (P28370)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: SMARCA1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1054 Hs			1 183
+	Hs
		658650 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		229384 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027145 CHD5_HUMAN (31-961): 0: 800: 28.13		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1018451 CHD3_HUMAN (31-954): 0: 791: 28.94		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027001 CHD4_HUMAN (29-960): 0: 789: 28.27		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1161080 CHD4_MOUSE (29-960): 0: 787: 28.27		Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027300 CHD7_HUMAN (3-1046): 0: 780: 26.74		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027277 CHD8_HUMAN (2-1011): 0: 769: 27.72		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800360 CHD3_HUMAN (31-954): 0: 791: 28.94		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		800380 CHD4_HUMAN (29-960): 0: 789: 28.27		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949764 CHD3_HUMAN (31-954): 0: 791: 28.94		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		949784 CHD4_HUMAN (29-960): 0: 789: 28.27		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		949943 CHD4_MOUSE (29-960): 0: 787: 28.27		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		1027026 CHD9_HUMAN (2-1019): 0: 741: 26.94		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		203687 CHD4_HUMAN (29-960): 0: 789: 28.27		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		151406 CHD1_HUMAN (5-1050): 0: 695: 29.33		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		123245 CHD3_HUMAN (31-954): 0: 791: 28.94		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		123332 CHD7_HUMAN (3-1046): 0: 780: 26.74		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		800320 SMCA4_HUMAN (60-913): 0: 686: 31.42		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		846923 SMCA4_HUMAN (60-913): 0: 686: 31.42		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33