HitPredict

Interactor 1: 5HT1E (P28566)
5-hydroxytryptamine receptor 1E (5-HT-1E) (5-HT1E) (S31) (Serotonin receptor 1E)
Gene: HTR1E

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 375
+	Hs
		659335 5HT1E_HUMAN (1-365): 8.36e-76: 240: 100.00		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		429013 ADRB2_HUMAN (1-365): 2.15e-76: 242: 28.30		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		626680 ADA1D_HUMAN (19-355): 3.9e-77: 249: 26.84		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Hs
		839269 5HT6R_HUMAN (4-363): 2.61e-61: 204: 27.55		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		658219 5HT2C_HUMAN (42-361): 1.24e-64: 214: 30.89		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Hs
		149793 OR7AH_HUMAN (2-290): 1.1e-61: 201: 15.18		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		149794 OR7AH_HUMAN (2-290): 1.1e-61: 201: 15.18		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		915523 OR1A1_HUMAN (2-294): 1.49e-60: 199: 14.33		ACTA_HUMAN (2-375): 0: 591: 94.12