HitPredict

Interactor 1: MAX (P28574)
Protein max (Myc-associated factor X) (Myc-binding novel HLH/LZ protein) (Protein myn)
Gene: MAX

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	17296600, 20946988
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0071339 - MLL1 complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 160 Mm			1 336
+	Hs
		898178 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		347679 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		379766 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		898110 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		346606 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		379317 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		898188 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Mm
		659354 MAX_MOUSE (1-160): 1.21e-31: 112: 100.00		PCGF6_MOUSE (31-293): 9.54e-43: 152: 16.17
+	Hs
		347818 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Hs
		584889 SRBP1_HUMAN (9-149): 7.47e-29: 113: 23.08		RO52_HUMAN (36-249): 1.63e-36: 139: 13.08
+	Hs
		585632 TFE3_HUMAN (11-147): 1.64e-24: 100: 19.72		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		347823 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		TRI55_HUMAN (42-318): 5.67e-37: 141: 13.42
+	Hs
		379067 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		345897 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RO52_HUMAN (36-249): 1.63e-36: 139: 13.08
+	Hs
		346112 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		347755 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Hs
		749531 USF2_HUMAN (14-113): 2.14e-24: 98.4: 33.95		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		347835 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		TRIM6_HUMAN (38-292): 1.25e-31: 125: 13.28
+	Hs
		345841 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RAG1_HUMAN (42-197): 7.03e-29: 119: 20.51